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In General
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In research, the Institute of Pathology and Forensic Veterinary
Medicine focuses on neuropathology and infectious diseases.
The resulting research projects are conducted by faculty and
staff members together with graduate and postgraduate students.
In many projects there is an intensive cooperation with intra-
or extramural partners.
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Projects Neuropathology
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- Adult neurogenesis
- Neuroprotection after cardiac arrest
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Projekte Infektionsmedizin
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- Pathogenicity of various Mycoplasma species in the respiratory
tract of different animal species
- Pathology, pathogenesis and epidemiology of emerging infectious
diseases
- Novel tools for identification of protozoa
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Research
foci:
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Adult neurogenesis
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With different molecular and histochemical techniques we perform
cell cycle studies on nerve cells of brain tissue of cats. Investigations
on nerve cell cultures and slice cultures of hippocampus and
other brain regions should enable insights into the potential
mitotic activity of adult neurons and yield broader approaches
for the research of neuronal metabolism.
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| Involved scientists: |
Dr. Angelika Url |
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Dr. Barbara Rebel-Bauder |
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Graduate and postgraduate students |
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Neuroprotection after
cardiac arrest
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Using animal models (pig and rat) the effects of mild hypothermia
on neuropathological changes after cardiac arrest and reperfusion
are investigated. The optimal time point and the best method
for induction of hypothermia should be determined.
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| Involved scientists: |
Prof. Dr. Peter Schmidt |
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Dr. Sandra Högler |
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Mag. René Brunthaler |
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Graduate and postgraduate students |
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| Cooperation partners:
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Prof. Sterz, Department für
Notfallmedizin, Med. Uni Wien |
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Prof. Sipos, Klinik für
Schweine, VetMedUni Vienna |
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| Funding: |
FWF - Austrian Science Fund |
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Hochschuljubiläumsstiftung
der Stadt Wien |
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Pathogenicity of various
Mycoplasma species
in the respiratory
tract of different
animal species
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Mycoplasma are often isolated from the respiratory tract of
animals with respiratory diseases. Frequently their pathogenic
role remains unclear.
With the aid of immunohistochemistry using antibodies against
a number of different Mycoplasma species we intend to analyse
whether these bacteria are concentrated in pneumonic lesions
and thus likely to play a causative role. Currently, pneumonias
of pigs, cats, dogs and different bird species are investigated.
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| Involved scientists: |
Prof. Dr.Herbert Weissenböck |
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Dr. Barbara Richter |
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Ingrid Friedl |
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Graduate and postgraduate students |
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| Cooperation partners:
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Institute of Bacteriology und
Hygiene, University of Veterinary |
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| Funding: |
Hochschuljubiläumsstiftung
der Stadt Wien |
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Pathology, pathogenesis and
epidemiology of emerging
infectious diseases
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Dead animals submitted for necropsy are frequently the initial
event for recognizing and follow-up investigations of emerging
diseases (examples: Usutu virus and West Nile virus infections
in Austria). In some cases the recognition of a novel condition
will initiate surveillance programs which provide data on incidence,
epidemiology and general relevance of such diseases.
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| Involved scientists: |
Prof. Dr.Herbert Weissenböck |
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Nora Nedorost |
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Mag. Natalie Alexandrow |
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| Cooperation partners:
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Clinical Virology, University
of Veterinary Medicine |
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Department of Veterinary Microbiology,
University of Budapest |
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Institute of Vertebrate Biology,
Czech Academy of Sciences |
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Novel tools for identification
of protozoa
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By using "custom-made" oligonucleotide probes and
the chromogenic in situ hybridization we develop novel diagnostic
approaches for a number of protozoa and other single-celled
eukaryotes. The probes are subjected to rigorous tests for specificity
and represent novel tools in diagnostics and pathogenesis research.
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| Involved scientists: |
Prof. Dr.Herbert Weissenböck |
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Dr. Barbara Richter |
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Mag. Nora Dinhopl |
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Karin Fragner |
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| Funding: |
FWF - Austrian Science Fund |
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